Clinical trial · Interventional
Individually Tailored Training Prescriptions in Cancer Patients: The TOP Study
NCT02883699CI-TRIAL-00044361TOPcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The TOP Study is a two-stage study on individually tailored endurance and resistance training prescriptions for breast and prostate cancer patients after the end of primary therapy in order to optimize training effects.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Daily undulating periodization resistance training | Behavioral | — | UNRESOLVED |
| Polarized endurance training | Behavioral | — | UNRESOLVED |
| Standard endurance training | Behavioral | — | UNRESOLVED |
| Standard resistance training | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Endurance Training Group 1
- description
- Standard endurance training
- interventionNames
- Behavioral: Standard endurance training
- type
- EXPERIMENTAL
- label
- Endurance Training Group 2
- description
- Polarized endurance training
- interventionNames
- Behavioral: Polarized endurance training
- type
- ACTIVE_COMPARATOR
- label
- Resistance Training Group 1
- description
- Standard resistance training
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosed with early stage breast cancer (M0) or prostate cancer (M0 or M1 with PSA evidence of stable disease) * 6 to 52 weeks after the end of primary therapy * ≥18 to 75 years of age * no regular endurance or resistance training (≥ one session per week) since diagnosis or within the last 6 months * sufficient German language skills * willing/ able to train at the provided exercise facilities twice per week and to take part in the scheduled testing * signed informed consent. Exclusion Criteria: * diagnosed with additional other cancer * brain or bone metastases in M1 prostate cancer patients * heart failure \>NYHA III, unstable angina pectoris or severe arrhythmia * uncontrolled hypertension * reduced standing or walking ability * any other comorbidities that preclude participation in exercise testing or training.
References
Publications (1)
- DERIVEDPelzer F, Leisge K, Schluter K, Schneider J, Wiskemann J, Rosenberger F. Effects of exercise mode and intensity on patient-reported outcomes in cancer survivors: a four-arm intervention trial. Support Care Cancer. 2023 May 2;31(5):315. doi: 10.1007/s00520-023-07757-9. PMID 37129687