Clinical trial · Observational
Effect on Patient Reported Outcomes of VATS and SABR (LILAC)
Curative Treatment Modalities of Early Stages Non-Small Cell Lung Cancer: Effect on Patient Reported Outcomes of Video Assisted Thoracoscopic (VATS) Resection and Stereotactic Ablative Body Radiotherapy (SABR)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will monitor the effect on patients reported outcomes (PROMs) of VATS resection and SABR for NSCLC delivered at the Leeds Cancer Centre The investigator will support with this information the Shared Decision Making (SDM) process. 300 consecutive patients will be followed up from prior the treatment to 12 months afterwards, administering multiple questionnaires (EORTC QLQ C-30 and LC-13, PSQ-18, Decision Self-Efficacy Scale) by a remote web-based system. Deliverable: 1. Differences after VATS resections or SABR in terms of physical and psychological symptoms, quality of life and satisfaction 2. Patient perspectives of the Shared Decision Making Process.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Decision Self-Efficacy Scale | Other | — | UNRESOLVED |
| EORTC QLQ-C30 (version 3.0). | Other | — | UNRESOLVED |
| PS Q18 | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Surgical Patients
- description
- Early stage NSCLC patients submitted to Surgical Resection
- interventionNames
- Other: EORTC QLQ-C30 (version 3.0).
- Other: PS Q18
- Other: Decision Self-Efficacy Scale
- label
- SABR Patients
- description
- Early stage NSCLC patients submitted to SABR
- interventionNames
- Other: EORTC QLQ-C30 (version 3.0).
- Other: PS Q18
- Other: Decision Self-Efficacy Scale
Primary outcomes (1)
- measure
- Patients Reported Outcomes
- timeFrame
- 12 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 years and over. * Diagnosis of NSCLC either from histology or MDT/Tumour Board agreement on \>95% likelihood of diagnosis based on radiological evidence or both. * Decision for either surgery or SABR * Able to give informed consent. * Able to understand the language of the questionnaire. * There will be no limit on performance status. Exclusion Criteria: * Advanced diseases (III-IV stages). * Patient included in other HRQoL study, which may increase patient burden and bias the answer of the questionnaires.
References
Publications (1)
- DERIVEDPompili C, Franks KN, Brunelli A, Hussain YS, Holch P, Callister ME, Robson JM, Papagiannopoulos K, Velikova G. Patient reported outcomes following video assisted thoracoscopic (VATS) resection or stereotactic ablative body radiotherapy (SABR) for treatment of non-small cell lung cancer: protocol for an observational pilot study (LiLAC). J Thorac Dis. 2017 Aug;9(8):2703-2713. doi: 10.21037/jtd.2017.07.35. PMID 28932579