Clinical trial · Interventional
Study of Trans-tissular Migration of Macrophages Associated to Human Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Surgical samples of human primitive breast: Representative and various surgical samples of human primitive breast carcinoma in terms of histological type. Moreover, healthy tissue from the same patient will be analysed in parallel. Adjacent normal epithelial structures will be defined as at least 5 mm away from the tumor and histologically normal in appearance. Isolation, differentiation of human monocyte-derived Macrophages (Mphs) and determination of the Macrophage (Mph) migration mode : Human Mphs will be differentiated from blood monocytes isolated from the same patient than the tumor sample. Blood samples will be obtained following standard ethical procedures.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Define macrophages migration mode | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Study arm
- interventionNames
- Other: Define macrophages migration mode
Primary outcomes (2)
- measure
- Analysis of Breast Tumor sample
- timeFrame
- up to 2 years
- description
- analysis of the sensitivity to inhibitors
- measure
- Analysis of Breast Tumor sample
- timeFrame
- up to 2 years
- description
- analysis of the cell morphology
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Female patient with breast cancer 2. Age \> 18 years old 3. Available primary breast tumor sample with adjacent normal epithelial structures 4. Informed consent obtained and signed Exclusion Criteria: 1. Primary tumor size \< 1cm 2. Surgical tumor sample without available adjacent normal epithelial structures
References
Publications (0)
Data not yet available