Clinical trial · Interventional
ROLL vs WGLL for Non-palpable Breast Lesions
Radioguided Occult Lesion Localization (ROLL) is Superior a to the Wire-Guided Lesion Localization (WGLL)? Randomized Controlled Clinical Trial
NCT02869230CI-TRIAL-00023511ROLLvsWGLLcompletedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Here were present a controlled clinical trial comparing wire-guided lesion localization (WGLL)and radioguided occult lesion localization (ROLL) in patients treated for nonpalpable breast lesions at the Instituto Nacional de Cancerología (National Cancer Institute)in Bogotá,Colombia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ROLL | Procedure | — | UNRESOLVED |
| wire-guided lesion localization | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Radioguided occult lesion localization
- description
- The ROLL technique (radioguided occult lesion localization) is characterized by the injection of a radiotracer in the center of the lesion
- interventionNames
- Procedure: ROLL
- type
- EXPERIMENTAL
- label
- wire-guided lesion localization
- description
- wire-guided lesion localization, including better lesion centricity in relation to margins,decreased marking time, reduced surgery time, and better aesthetic outcomes
- interventionNames
- Procedure: wire-guided lesion localization
Primary outcomes (1)
- measure
- Localization of nonpalpable breast lesion (percentage)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients older than 18 years * Lesions suggesting malignancy (BIRADS 4 and 5) * Solid nodules in postmenopausal women (BIRADS 3 mammograms). Exclusion Criteria: * Pregnant or nursing * Patients with suspected multifocal or multicentric disease (suspicious microcalcifications scattered over a wide area on mammography) * Patients with retro-areola lesions (less than 2 cm away from the nipple) * Lesions that had previously undergone surgery or excisional biopsies in the compromised breast
References
Publications (0)
Data not yet available
No reference posted for this study.