Clinical trial · Interventional
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine for Postoperative Analgesia in Children Undergoing Major Abdominal Cancer Surgery
NCT02861716CI-TRIAL-00032446unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study the investigators aim to determine the analgesic effect and side effects of intrathecal fentanyl and dexmedetomidine as adjuvant to local anesthetics in pediatric patients undergoing major abdominal cancer surgeries.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Intrathecal Dexmedetomidine | — | UNRESOLVED | — |
| Pediatric Cancer Surgery | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bupivacaine | Drug | — | UNRESOLVED |
| Dexmedetomidine | Drug | — | UNRESOLVED |
| Fentanyl | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- fentanyl and dexmedetomidine
- description
- intrathecal bupivacaine (0.5%) 0.4mg/kg plus fentanyl and dexmedetomidine in 2ml volume will be injected slowly over 20 seconds.
- interventionNames
- Drug: Bupivacaine
- type
- ACTIVE_COMPARATOR
- label
- dexmedetomidine and placebo for fentanyl
- description
- intrathecal bupivacaine (0.5%) 0.4mg/kg plus dexmedetomidine 0.2 μg/kg in 2ml volume and placebo (for fentanyl 0.2 μg/kg) it will be injected slowly over 20 seconds.
- interventionNames
- Drug: Bupivacaine
- Drug: Dexmedetomidine
- type
- ACTIVE_COMPARATOR
- label
- fentanyl and placebo for dexmedetomidine
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 3 Years
- Maximum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status I and II * Patients scheduled for major abdominal cancer surgeries, expected to last more than 90 minutes Exclusion Criteria: * Sacral bone abnormalities * Spina bifida * Coagulopathy * Mental delay or retardation * Known allergy to the study drugs * Local infection at the site of injection
References
Publications (0)
Data not yet available
No reference posted for this study.