Clinical trial · Interventional
The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ARDS (Acute Respiratory Distress Syndrome) | — | UNRESOLVED | — |
| Bronchiectasis | — | UNRESOLVED | — |
| COPD (Chronic Obstructive Pulmonary Disease) | — | UNRESOLVED | — |
| Interstitial Pulmonary Fibrosis ARDS | — | UNRESOLVED | — |
| Lymphangioleiomyomatosis | Lymphangioleiomyomatosis | ONTOLOGY_EXACT | 0.98 |
| Primary Pulmonary Hypertension | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Veno-veno-arterial ECMO | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Veno-veno-arterial ECMO group
- interventionNames
- Procedure: Veno-veno-arterial ECMO
Primary outcomes (4)
- measure
- arterial blood oxygen partial pressure (PaO2)
- timeFrame
- 5 min after jugular catheter flow 0ml/min
- measure
- arterial blood oxygen partial pressure (PaO2)
- timeFrame
- 5 min after jugular catheter flow 500 ml/min
- measure
- arterial blood oxygen partial pressure (PaO2)
- timeFrame
- 5 min after jugular catheter flow 1,000ml/min
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1\. scheduled for double lung transplantation Exclusion Criteria: 1. patients who have history of coronary artery occlusive disease 2. patients with arrhythmia
References
Publications (0)
Data not yet available