Clinical trial · Observational
Progesterone Induced Blocking Factor Expression Levels in Endometrial Cancer Cells.
Determining Levels of Expression of Progesterone-Induced Blocking Factor in Endometrial Cancer Cells.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Immune system suppression effect of Progesterone Induced Blocking Factor(PIBF), it could be questionable whether tumor cells express PIBF for escape of immune system. There are some studies in the literature that evaluate PIBF expression of different malign cells (e.g. glioblastoma multiforme as a malign central nerve system, leukemia, astrocytoma as a primary brain tumor, lung cancer and chorionic carcinoma). According to previous studies PIBF has been used as an anti-tumor immune suppressor by tumor cells. There is no data about the PIBF expression of endometrial tumor cells. Therefore, the investigators aim to determine the PIBF expression levels in the endometrial cancer cells.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Progesterone Induced Blocking Factor in Endometrial Cancer | Endometrial Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (3)
- label
- study group1
- description
- 20 paraffin embedded blocks which was diagnosed endometrial cancer
- label
- control group
- description
- 20 paraffin embedded blocks of healthy women
- label
- study group2
- description
- 20 paraffin embedded blocks which was diagnosed endometrial hyperplasia
Primary outcomes (1)
- measure
- Immunohistochemically Levels of PIBF in Endometrial Cancer Cells
- timeFrame
- 3 months
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosed endometrial cancer * diagnosed endometrial hyperplasia Exclusion Criteria: * diagnosed cancer except endometrial cancer
References
Publications (0)
Data not yet available