Clinical trial · Interventional
Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness
NCT02844504CI-TRIAL-00047483completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Breast cancer patients often suffer from long-term physical symptoms of weakness. In this study, investigators propose to compare how two different low intensity physical exercise training programs can improve handgrip strength for breast cancer patients with symptoms of weakness. Using brain imaging, the study will also investigate changes in brain structure, and muscle activity associated with handgrip.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Low Intensity Exercise Training 1 | Behavioral | — | UNRESOLVED |
| Low Intensity Exercise Training 2 | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Low Intensity Exercise Training 1
- description
- Cancer survivors will receive low intensity handgrip exercise training.
- interventionNames
- Behavioral: Low Intensity Exercise Training 1
- type
- EXPERIMENTAL
- label
- Low Intensity Exercise Training 2
- description
- Cancer survivors will receive low intensity handgrip exercise training different than other arm.
- interventionNames
- Behavioral: Low Intensity Exercise Training 2
- type
- NO_INTERVENTION
- label
- Control
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 40 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Female aged 40-75 yrs * Right handed, as determined by the Edinburgh Inventory (Oldfield, 1971) * Proficient in English * Must be available for the familiarization, and testing sessions Exclusion Criteria: * Symptoms for mild or severe depression as determined by a Patient Health Questionnaire (PHQ-8) score \>14 * Significant cognitive impairments as defined by a score \<28 in the Folstein Mini-Mental Screening Examination (MMSE, Folstein et al .1975). * Participated in any type of motor imagery or strength training program in the last 5 years, or plan to start any motor imagery or physical strength training program for the 3 months duration of the study * Neurological, psychiatric, musculoskeletal or other types of disorder that may affect participants sensorimotor function and cognitive abilities * Current medication believed to affect cognitive/psychomotor function (i.e., opioid, analgesics, anxiolytics or antidepressants) * History of alcohol, smoking, and drug abuse * Any contraindication for MRI
References
Publications (0)
Data not yet available
No reference posted for this study.