Clinical trial · Interventional
The Effect of Pre-treatment Biopsy for Non-neoplastic Renal Disease vs no Biopsy on Estimated Glomerular Filtration Rate in Patients With Small Renal Mass: a Single-center, Single-blinded, Randomized, Parallel Group Clinical Trial
NCT02841020CI-TRIAL-00035521withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Funding for study fell through
Summary
Brief summary (as posted)
The purpose of this study is to determine if biopsy for non-neoplastic renal disease for patients with a small renal mass results in greater postoperative renal function than the current standard of care (no additional biopsy).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Kidney Neoplasms | Kidney Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Additional biopsy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control SOC
- description
- Standard of care is followed
- type
- EXPERIMENTAL
- label
- Experimental additional biopsy
- description
- Additional biopsy
- interventionNames
- Procedure: Additional biopsy
Primary outcomes (1)
- measure
- difference in change in glomerular filtration rate (GFR)
- timeFrame
- 6 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 or greater * Scheduled for renal biopsy as part of clinical care * Diagnosis of small renal mass (\< 4cm) based on imaging (CT, MRI, Ultrasound, or other) * Patient must provide written, informed consent for study procedures before randomization * Renal mass must be primarily solid (as opposed to cystic) in nature Exclusion Criteria: * Patients less than 18 years of age * Patients who are prisoners * Women who are pregnant-self reported * Patients with Bosniak 3 or 4 cystic renal masses * Patients with history of renal transplantation * Patients with eGFR less than 30-based on review of clinical labs * Patients on dialysis * Patients with bleeding disorders
References
Publications (0)
Data not yet available
No reference posted for this study.