Clinical trial · Interventional
Serratus Plane Block for the Prevention of Chronic Pain After Breast Cancer Surgery
NCT02838173CI-TRIAL-00023154unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study compare the "Serratus block plane" (SPB) and the local infiltration of the tissue in the prevention of acute and chronic pain after breast cancer surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast/Surgery | — | UNRESOLVED | — |
| Chronic Pain | — | UNRESOLVED | — |
| Postoperative Complication | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| serratus plane bloc : placebo | Procedure | — | UNRESOLVED |
| serratus plane bloc : Ropivacaine 2mg/ml (0,3ml/kg) | Procedure | — | UNRESOLVED |
| tissue infiltration : placebo | Procedure | — | UNRESOLVED |
| tissue infiltration : Ropivacaine 2mg/ml (0,3ml/kg) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- SPB
- description
- Serratus Plane Bloc with Ropivacaine 2mg/ml (0,3ml/kg) and tissue infiltration with placebo made once, by the anesthetist in the operating theater before surgical incision
- interventionNames
- Procedure: serratus plane bloc : Ropivacaine 2mg/ml (0,3ml/kg)
- Procedure: tissue infiltration : placebo
- type
- ACTIVE_COMPARATOR
- label
- tissue infiltration
- description
- tissue infiltration with Ropivacaine 2mg/ml (0,3ml/kg) and Serratus Plane Bloc with placebo made once, by the anesthetist in the operating theater before surgical incision
- interventionNames
- Procedure: tissue infiltration : Ropivacaine 2mg/ml (0,3ml/kg)
- Procedure: serratus plane bloc : placebo
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Women scheduled for elective breast neoplasm surgery * Of ASA classification 1, 2 or 3 * Patients who provide written informed consent Exclusion Criteria: * Minor patients * Patients refusing to sign the consent * Patients included in another protocol within 3 months * Pregnant or lactating patients * Patients with history of allergy to local anesthetics (Ropivacaine) * Patients with contraindication to regional anesthesia (coagulopathy, local infection ...) * Patients with history of prior breast surgery (excluding diagnostic biopsy) * Patients with history of chronic pain * Patients with a history of psychiatric disorder
References
Publications (2)
- BACKGROUNDBlanco R, Parras T, McDonnell JG, Prats-Galino A. Serratus plane block: a novel ultrasound-guided thoracic wall nerve block. Anaesthesia. 2013 Nov;68(11):1107-13. doi: 10.1111/anae.12344. Epub 2013 Aug 7. PMID 23923989
- BACKGROUNDAndreae MH, Andreae DA. Regional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysis. Br J Anaesth. 2013 Nov;111(5):711-20. doi: 10.1093/bja/aet213. Epub 2013 Jun 28. PMID 23811426