Pelvic External Combined With 252-Cf Neutron Intracavitary Radiotherapy With or Without Platinum in Treating Advanced Cervical Cancer

Inclusion Criteria:

* 1\. To be aged from 18 (including 18) to 65 (including 65), female patient;
* 2\. Expected survival ≥6 months
* 3\. Pathologically proven diagnosis of squamous carcinoma or adenocarcinoma of the cervix, according to FIGO(International Federation of Gynecology and Obstetrics) staging, appropriate stage for protocol entry, including IIA2, IIB,IIIA,IIIB;
* 4\. No patients with distant metastases;
* 5\. Measurable target lesions (satisfying the criteria in RECIST 1.1);
* 6\. ECOG PS status of 0-2;
* 7\. No prior treatment;
* 8\. No
* 9\. No surgery
* 10\. Major organ function has to meet the following criteria:

  1. Bilirubin \<1.5 times the upper limit of normal (ULN)
  2. ALT , AST and APL≤2.5 × ULN
  3. NEUT≥2.0 × 10\^9 / L
  4. PLT ≥ 100 × 10\^9 / L
  5. HB≥60g/L
  6. Serum Cr and urea nitrogen ≤ 1.5 × ULN
* 11\. Favorable cardiac functions, no patients with myocardial infarction within half a year, hypertension and coronary disease are well-controlled.

Exclusion Criteria:

* 1\. Serious heart disease, pulmonary disease, hepatic disease, , renal disease and metabolic disease, or with electrolyte disturbance;
* 2\. Allergic to platinum;
* 3\. Rejecte to join the study in other conditions.