Clinical trial · Interventional
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical ventilation. Among various surgical positions, the prone position is known to cause unique physiologic and hemodynamic changes and affect the predictability and cut-off values of dynamic indices for fluid responsiveness. A previous study reported that pulse pressure variation (PPV) and corrected flow time were able to predict fluid responsiveness with relatively high accuracy in patients undergoing spine surgery in the prone position using a Wilson frame. However, the Jackson frame is known to have less effects on the cardiovascular system compared to the Wilson frame, and therefore may be physiologically more appropriate in patients undergoing surgery in the prone position. The pleth variability index (PVI) is a dynamic index that can be monitored non-invasively in patients under mechanical ventilation. The present study aims evaluate the validity of PPV and pleth variability index (PVI) as predictors of fluid responsiveness in the supine and prone positions in patients undergoing posterior lumbar spinal fusion using the Jackson table.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis | — | UNRESOLVED | — |
| Scoliosis or Tumors | — | UNRESOLVED | — |
| Spinal Fractures | — | UNRESOLVED | — |
| Spondylolisthesis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Philips Intelivue MP70 monitor | Device | — | UNRESOLVED |
| Pleth Variability Index (PVI) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Fluid loading group
- interventionNames
- Device: Philips Intelivue MP70 monitor
- Device: Pleth Variability Index (PVI)
Primary outcomes (2)
- measure
- Pulse Pressure Variation (PPV)
- timeFrame
- From 15 minutes after induction of anesthesia in the supine position to 5 minutes after fluid loading in the prone position
- description
- Fluid responsiveness predictability of FTc and PVI in patients undergoing posterior lumbar fusion in the prone position by using the Jackson frame by calculating area under the curve of the ROC curve.
- measure
- Pleth Variability Index (PVI)
- timeFrame
- From 15 minutes after induction of anesthesia in the supine position to 5 minutes after fluid loading in the prone position
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1\. Patients between the age of 19 and 75, scheduled for spine surgery under general anesthesia using the Jackson table Exclusion Criteria: 1. Patient refusal 2. Patients that are not normal sinus rhythm on preoperative ECG 3. Patients with moderate\~severe cardiac valve disease 4. Patients with an ejection fraction under 50% 5. Significant lung disease 6. Obesity (BMI\>35kg/m2) 7. Patients with contraindications to esophageal doppler probe insertion 8. Illiterate patients or foreigners
References
Publications (0)
Data not yet available