Clinical trial · Observational
Acute Pain Trajectories and Persistent Pain After Breast Cancer Surgery
Acute Pain Trajectories as a Predictive Factor for Persistent Pain After Breast Cancer Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Persistent pain after breast cancer surgery (PPBCS) is a significant clinical problem, affecting between 25 and 50% of patients. Several factors are associated with the development of PPBCS, including acute postoperative pain. The analysis of pain trajectories through mixed model modeling is an alternative to static pain measures, improving precision and providing information on the time course of pain resolution. Our aim was to investigate if the characteristics of pain trajectories during the first postoperative week are correlated with the persistence of pain 3 months after breast cancer surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Study population
- description
- The study population consists of adult surgery patients, scheduled for breast cancer surgery at St-Luc University Hospital.
Primary outcomes (1)
- measure
- Presence of pain 3 months after surgery, assessed with the Brief Pain Inventory questionnaire. Yes/No
- timeFrame
- 3 months
Secondary outcomes (1)
- measure
- Acute pain trajectories (7 days) after surgery
- timeFrame
- One postoperative week
- description
- The pain trajectory is the vector of 7 verbal numerical pain scores (from 0 to 10) recorded in a pain diary over the first 7 postoperative days
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Scheduled for breast cancer surgery * General anesthesia Exclusion Criteria: * Previous breast surgery * Reconstructive surgery scheduled during follow-up * Day-surgery patients * Inability to understand the questionnaires
References
Publications (0)
Data not yet available