Clinical trial · Observational
CT Colonography as the Initial Diagnostic Imaging Tool for Patients With Suspected Colorectal Cancer
Observational Study to Compare the Utilisation of CT Colonography With Optical Colonoscopy as the First Diagnostic Imaging Tool in Patients With Suspected Colorectal Cancer
NCT02820389CI-TRIAL-00028977CTCSunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to evaluate whether the use of Computed Tomography Colonography (CTC) for patients with low to intermediate risk of suspected colorectal cancer decreases overall NHS costs and waiting times whilst increasing patient satisfaction compared to clinical practice with utilisation of Optical Colonoscopy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CTC | Procedure | — | UNRESOLVED |
| Optical colonoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Optical colonoscopy
- description
- Patients with suspected colorectal cancer will undergo optical colonoscopy as the initial imaging modality.
- interventionNames
- Procedure: Optical colonoscopy
- label
- CT Colonography
- description
- Patients with suspected colorectal cancer will undergo Computed Tomography Colonography (CTC) as the initial imaging modality. Subsequent imaging might be required based on the findings from the CTC scan.
- interventionNames
- Procedure: CTC
Primary outcomes (1)
- measure
- 3-month cost analysis per patient undergoing either Optical Colonoscopy or CTC as the initial imaging modality (measured in £ per patient)
- timeFrame
- 3 months following the initial imaging modality (either CTC or Optical Colonoscopy)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Every adult patient over 40 years old, presenting with constipation or alternating change in bowel habits, with a differential diagnosis of suspected colorectal cancer. Exclusion Criteria: * Patients presenting with anaemia; * Patients presenting with diarrhoea only for more than 6 weeks; * Patients presenting with rectal bleeding; * Patients who have undergone a previous whole-colon examination in the past 6 months; * Patients who have been referred for a whole-colon examination to follow up already diagnosed colorectal cancer; * Patients lacking capacity to give consent or participate in the study; * Patients already taking part in any clinical trial of an investigational medicinal product (CTIMP); * Prisoners * Patients who are not fluent in English.
References
Publications (0)
Data not yet available
No reference posted for this study.