Clinical trial · Interventional
Safety of 250ml Preoperative Carbohydrate Drink in Gastric Cancer Patients
Safety and Effectiveness of Oral Administration of 5% Glucose Solution 250ml 2-3 Hours Before Surgery in Gastric Cancer Patients for Elective Radical Resection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to assess the impact of preoperative oral carbohydrate drink on gastric emptying and PH of gastric fluid in gastric cancer patients directly. Furthermore, investigators aim to evaluate the safety and effectiveness of preoperative oral carbohydrate in elective gastric cancer surgery, providing direct evidence for clinical practice.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| preoperative oral carbohydrate drink | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Treatment group
- description
- Preoperative oral carbohydrate drink: patients drink 5% glucose solution 250ml 2-3 hours before surgery.
- interventionNames
- Dietary Supplement: preoperative oral carbohydrate drink
- type
- NO_INTERVENTION
- label
- Control group
- description
- Patients undergo 6-8 hours of preoperative fasting.
Primary outcomes (1)
- measure
- preoperative gastric residual volume of gastric fluid
- timeFrame
- 20-30 minutes before the surgery
- description
- After anesthesia induction with 100-120mg propofol and 0.5 mg/kg rocuronium bromide and tracheal intubation, keep the patient in left lateral decubitus position. Insert the gastroscope ( Olympus 260) and perform complete suction of gastric fluid under direct vision with the suction apparatus connecting to the sterile airtight collector. Measure the volume of the gastric fluid in collector with a cylindrical measuring cup, accurate to 0.1ml. Repeat it and then take an average.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Age between 18 and 80 years * Histologically confirmed gastric adenocarcinoma * Tumor of cT2-4aN0-2 in preoperative gastroscopy, endoscopic ultrasound, and/or abdominal computed tomography * Fit for elective radical resection * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 * American Society of Anesthesiology (ASA) status I to III * Body mass index (BMI) of 17.5-27.5 kg/m2 .Patient agreed to participate this trial through informed consent. Exclusion Criteria: * Symptoms of pyloric obstruction * Impaired bowel function, using drugs disturbing gastric secretion and gastric emptying * History of gastric resection * History of gastric cancer treatment * History of major abdominal operation, or diffuse peritonitis * Diabetes or impaired glucose tolerance, or with abnormality in other endocrine hormones * Potential difficult airway as evaluated by anesthesiologist * Pregnancy or breastfeeding were excluded in this trial .Patients would also be excluded if the following circumstances occurred: (1) failure of endotracheal intubation; (2) failure of intra-operative gastroscopy; or (3) irresectable tumor.
References
Publications (0)
Data not yet available