Clinical trial · Observational
Comparison of 22-gauge and 19-gauge Aspiration Needle During EBUS-TBNA
Comparison of the Diagnostic Yield Between Various Endobronchial Ultrasound-guided-transbronchial Needles (EBUS-TBN) to Evaluate Suspect Mediastinal and Hilar Lymph Nodes
NCT02813603CI-TRIAL-00033743completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Investigators intend to compare the 19-gauge needle and the 22-gauge-needle during EBUS-TBNA concerning the diagnostic yield, the quality and quantity of each biopsy needle without raising the rate of complications.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EBUS | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Study Product (19-gauge)
- description
- After randomization, the subject undergo EBUS-TBNA either with the 19-gauge needle or the 22-gauge needle
- interventionNames
- Procedure: EBUS
- label
- Control Intervention (22-gauge)
- description
- After randomization, the subject undergo EBUS-TBNA either with the 19-gauge needle or the 22-gauge needle
- interventionNames
- Procedure: EBUS
Primary outcomes (1)
- measure
- sample weight
- timeFrame
- February 2017
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Male or female patients aged over 18 * Patients signed written informed consent * Mediastinal or hilar enlarged lymph nodes (\>10mm) in short axis radiological or clinical findings likely for lung cancer Exclusion Criteria: * Severe impairment of any organs, with do not enable anaesthesia * Quick \<80%, INR \>1,5, thrombocytes \<50/nl or PTT\>120sec * Other clinically relevant medical or psychological diseases, which affect the patients judgement or ability to participate in this study. * Insufficient language ability (spoken and written German)
References
Publications (1)
- DERIVEDWolters C, Darwiche K, Franzen D, Hager T, Bode-Lesnievska B, Kneuertz PJ, He K, Koenig M, Freitag L, Wei L, Eisenmann S, Taube C, Weinreich G, Oezkan F. A Prospective, Randomized Trial for the Comparison of 19-G and 22-G Endobronchial Ultrasound-Guided Transbronchial Aspiration Needles; Introducing a Novel End Point of Sample Weight Corrected for Blood Content. Clin Lung Cancer. 2019 May;20(3):e265-e273. doi: 10.1016/j.cllc.2019.02.019. Epub 2019 Mar 4. PMID 30914312