Clinical trial · Interventional
Conventional Laparoscopic APR Versus Laparoscopic APR With Transabdominal Individualized Levator Transection
Randomized Clinical Trial of Conventional Laparoscopic Abdominoperineal Resection (APR) Versus Laparoscopic APR With Transabdominal Individualized Levator Transection for Low Rectal Cancer
NCT02812628CI-TRIAL-00022722unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to compare the short-term and long-term benefits between conventional laparoscopic abdominoperineal resection (APR) and laparoscopic APR with transabdominal individualized levator transection (TILT).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LAPR | Procedure | — | UNRESOLVED |
| LAPR-TILT | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Conventional LAPR
- description
- Patients undergoing conventional laparoscopic abdominoperineal resection (LAPR).
- interventionNames
- Procedure: LAPR
- type
- EXPERIMENTAL
- label
- LAPR-TILT
- description
- Patients undergoing LAPR with transabdominal individualized levator transection (TILT).
- interventionNames
- Procedure: LAPR-TILT
Primary outcomes (1)
- measure
- 3-year local recurrence
- timeFrame
- 3 years post operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients diagnosed as having rectal cancer ≤5cm from anal verge by colonoscopy. 2. Patients undergoing elective, radial surgery with no distant metastasis. 3. Patients with Body Mass Index (BMI) between 18-30kg/m2. 4. Patients who agree to undergo standard adjuvant treatment after surgery. 5. Patients who have fully understood the aim of the trial and have signed the written informed consent. Exclusion Criteria: 1. Patients with distant metastasis, tumor infiltrating to adjacent organs, or recurrent tumors. 2. Patients undergoing emergent surgery. 3. Pregnant patients. 4. Patients with tumors other than rectal tumor. 5. Patients with severe comorbid diseases which preclude surgery. 6. Patients in bad conditions and do not ameliorate before surgery. 7. Patients undergoing other procedures to treat rectal cancer, eg. L-Dixon, L-Hartmann or Parks surgery. 8. Patients who refuse to accept standard adjuvant surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.