Clinical trial · Interventional
Low-dose Radiotherapy for Diffuse Large B-cell Lymphoma
A Phase II Trial of Low-Dose Radiotherapy for the Palliation of Patients With Diffuse Large B-cell Lymphoma
NCT02803840CI-TRIAL-00022621unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with Diffuse Large B-cell Lymphoma with indication for palliative radiotherapy are treated with low-dose radiation (2 x 2 Gy) to the symptomatic sites only. The primary endpoint of the study is the response rate and Quality of Life of the patients (QoL).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Low-dose radiotherapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Experimental
- description
- DLBCL patients with indication for palliative radiotherapy
- interventionNames
- Radiation: Low-dose radiotherapy
Primary outcomes (1)
- measure
- Response rate
- timeFrame
- Clinical response up to 21 days after treatment
- description
- Clinical response is defined as reduction \> 50% of maximum diameter of the radiated lesion
Secondary outcomes (1)
- measure
- Quality of life according to the EORTC QLQ-C30 questionnaire
- timeFrame
- The QLQ-C30 questionnaire is administered at baseline and at 21 days after treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with histologically proven diagnosis of DLBCL with indication for palliative radiotherapy Exclusion Criteria: * None
References
Publications (0)
Data not yet available
No reference posted for this study.