Clinical trial · Interventional
Comparing of Modified Wet Suction Technique and Dry Suction Technique for EUS-FNA of Solid Occupying Lesions
Comparing of Modified Wet Suction Technique and Dry Suction Technique for Endoscopic Ultrasound -Guided Fine Needle Aspiration (EUS-FNA) of Solid Occupying Lesions: a Prospective Multi-center,Randomized,and Controlled Trial
NCT02789371CI-TRIAL-00022504unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare the diagnosis accuracy of modified wet suction technique and 5ml dry suction technique on solid occupying lesions.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Infection | — | UNRESOLVED | — |
| Inflammation | — | UNRESOLVED | — |
| Lymphadenopathy | — | UNRESOLVED | — |
| Lymphatic Metastasis | — | UNRESOLVED | — |
| Neoplasm Metastases | — | UNRESOLVED | — |
| Pancreas Neoplasms | Pancreatic Neoplasm | ALIAS | 0.90 |
| Sarcoid | — | UNRESOLVED | — |
| Unknown Primary Neoplasm Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| the first pass is made with 5ml suction technique | Procedure | — | UNRESOLVED |
| the first pass is made with modified wet suction technique | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Arm A
- description
- the first pass is made with 5ml suction technique
- interventionNames
- Procedure: the first pass is made with 5ml suction technique
- type
- OTHER
- label
- Arm B
- description
- the first pass is made with modified wet suction technique
- interventionNames
- Procedure: the first pass is made with modified wet suction technique
Primary outcomes (1)
- measure
- the overall diagnostic accuracy of modified wet suction technique and 5ml dry suction technique to the solid occupying lesions
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age \>18 years old,\<80 years old; 2. Gender: Male or Female; 3. The patients who have solid occupying pancreatic lesions and non-pancreatic lesions (the diameter\>1cm) within the range of imaging examination(MRI、CT、B-type ultrasonography) and ultrasonic endoscope examination and should conduct the biopsy to identify lesion nature; 4. The patients who receive examinations in the research center; 5. The patients who sign the informed consent. Exclusion Criteria: 1. Hemoglobin≤8.0 g/dl; 2. Pregnant women; 3. The patients who have coagulation disorders（PLT\<50,000/mm3,INR\>1.5,roughly calculation, INR\>1.5, is equivalent to PT\>18 seconds); 4. The patients who took anticoagulants such as aspirin, warfarin in the latest week; 5. The patients who suffered from acute pancreatitis in the past two weeks; 6. The patients who have cardiopulmonary dysfunction, therefore cannot tolerate ultrasonic endoscope examination; 7. The patients who cannot sign the informed consent(such as patients who have mental disease or drug addiction and so on).
References
Publications (20)
- RESULTFurukawa H, Okada S, Kakizoe T. Early diagnosis of pancreatic cancer. Hepatogastroenterology. 1999 Jan-Feb;46(25):4-7. PMID 10228757
- RESULTFurukawa H, Okada S, Saisho H, Ariyama J, Karasawa E, Nakaizumi A, Nakazawa S, Murakami K, Kakizoe T. Clinicopathologic features of small pancreatic adenocarcinoma. A collective study. Cancer. 1996 Sep 1;78(5):986-90. doi: 10.1002/(SICI)1097-0142(19960901)78:53.0.CO;2-A. PMID 8780535
- RESULTDeWitt J, Jowell P, Leblanc J, McHenry L, McGreevy K, Cramer H, Volmar K, Sherman S, Gress F. EUS-guided FNA of pancreatic metastases: a multicenter experience. Gastrointest Endosc. 2005 May;61(6):689-96. doi: 10.1016/s0016-5107(05)00287-7. PMID 15855973
- RESULTPuli SR, Batapati Krishna Reddy J, Bechtold ML, Ibdah JA, Antillon D, Singh S, Olyaee M, Antillon MR. Endoscopic ultrasound: it's accuracy in evaluating mediastinal lymphadenopathy? A meta-analysis and systematic review. World J Gastroenterol. 2008 May 21;14(19):3028-37. doi: 10.3748/wjg.14.3028. PMID 18494054
- RESULTGress FG, Hawes RH, Savides TJ, Ikenberry SO, Lehman GA. Endoscopic ultrasound-guided fine-needle aspiration biopsy using linear array and radial scanning endosonography. Gastrointest Endosc. 1997 Mar;45(3):243-50. doi: 10.1016/s0016-5107(97)70266-9. PMID 9087830
- RESULTSavides TJ, Donohue M, Hunt G, Al-Haddad M, Aslanian H, Ben-Menachem T, Chen VK, Coyle W, Deutsch J, DeWitt J, Dhawan M, Eckardt A, Eloubeidi M, Esker A, Gordon SR, Gress F, Ikenberry S, Joyce AM, Klapman J, Lo S, Maluf-Filho F, Nickl N, Singh V, Wills J, Behling C. EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement. Gastrointest Endosc. 2007 Aug;66(2):277-82. doi: 10.1016/j.gie.2007.01.017. PMID 17643700
- RESULTSadeghi A, Mohamadnejad M, Islami F, Keshtkar A, Biglari M, Malekzadeh R, Eloubeidi MA. Diagnostic yield of EUS-guided FNA for malignant biliary stricture: a systematic review and meta-analysis. Gastrointest Endosc. 2016 Feb;83(2):290-8.e1. doi: 10.1016/j.gie.2015.09.024. Epub 2015 Sep 28.