Clinical trial · Observational
Identification and Referral of Women at Risk for Hereditary Breast/Ovarian Cancer
Strategies to Increase the Identification, Genetic Counseling Referral and Genetic Testing for Women at Risk for Hereditary Breast and/or Ovarian Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to identify the most effective means of follow-up for women who screen positive on B-RST (Breast Cancer Genetics Referral Screening Tool) applied in the standard clinical setting of mammography, to maximize the number who are referred to and receive cancer genetic counseling services. The clinical utility of B-RST 3.0 will also be evaluated by determining the number seen who are appropriate for genetic testing, undergo genetic testing and are found to carry a hereditary cancer gene mutations with medical management implications for the patient and family. The long-term goal is to reduce the morbidity and mortality associated with hereditary causes of breast and ovarian cancer among patients seen in the Emory/Winship system.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hereditary Breast and Ovarian Cancer | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Automatic Follow-Up by Genetic Counseling Staff | Other | — | UNRESOLVED |
| Breast Cancer Genetics Referral Screening Tool 3.0 | Other | — | UNRESOLVED |
| Physician Notification | Other | — | UNRESOLVED |
| Standard Handout | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Patient Initiated
- description
- Patients randomized into this group will receive a standard handout explaining their result, which includes information on how to obtain cancer genetics services through Winship. However, neither the patient nor their ordering clinician will be directly contacted regarding the B-RST result.
- interventionNames
- Other: Breast Cancer Genetics Referral Screening Tool 3.0
- Other: Standard Handout
- label
- Physician Notification
- description
- Patients randomized into this group will also receive the standard handout explaining their result. In addition, their primary care physician or ordering physician will be notified via Emory Electronic Medical Record (EeMR) that the patient screened positive on the B-RST. The note will provide specific instructions on how to refer the patient for cancer genetic counseling services.
- interventionNames
- Other: Breast Cancer Genetics Referral Screening Tool 3.0
- Other: Standard Handout
- Other: Physician Notification
- label
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient at one of the participating clinics (Winship Cancer Institute and Emory University Hospital Midtown) who arrive for a screening mammogram appointment. Exclusion Criteria: * Patients receiving a diagnostic mammogram will not be invited to participate in the study.
References
Publications (0)
Data not yet available