Clinical trial · Interventional
Endorings™ Assisted Colonoscopy Versus Standard Colonoscopy for Polyp Detection
Endorings™ Assisted Colonoscopy Versus Standard Colonoscopy for Polyp Detection in Symptomatic and Asymptomatic Patients: A Randomised Controlled Trial
NCT02785783CI-TRIAL-00036927Erings™completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates the impact of Endorings™ assisted colonoscopy on the number of polyps detected per patient compared to standard colonoscopy without use of EndoRings™. Half of the participants will receive EndoRings™ assisted colonoscopy, while the other half will receive standard colonoscopy.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasia | — | UNRESOLVED | — |
| Digestive Neoplasms | Digestive System Neoplasm | ALIAS | 0.90 |
| Digestive System Disease | — | UNRESOLVED | — |
| Gastrointestinal Disease | — | UNRESOLVED | — |
| Gastrointestinal Neoplasm | Digestive System Neoplasm | ALIAS | 0.90 |
| Intestinal Disease | — | UNRESOLVED | — |
| Intestinal Neoplasms | Intestinal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EndoRings™ | Device | — | UNRESOLVED |
| Standard colonoscopy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Standard colonoscopy
- description
- A standard colonoscope will be used to complete the procedure
- interventionNames
- Device: Standard colonoscopy
- type
- ACTIVE_COMPARATOR
- label
- EndoRings™
- description
- An EndoRings™ device will be placed at the distal end of a standard colonoscope
- interventionNames
- Device: EndoRings™
Primary outcomes (1)
- measure
- Number of polyps per patient
- timeFrame
- 14 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: * Symptomatic patients referred for colonoscopy age ≥ 55. * Asymptomatic patients age ≥55 undergoing screening or surveillance for polyps and cancers. Exclusion Criteria: * History of Inflammatory bowel disease * History of Hereditary non polyposis colorectal cancer (HNPCC) * Familial adenomatous polyposis syndrome (FAP) * Hyperplastic polyposis syndrome * Known colonic stricture
References
Publications (2)
- BACKGROUNDvan Rijn JC, Reitsma JB, Stoker J, Bossuyt PM, van Deventer SJ, Dekker E. Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol. 2006 Feb;101(2):343-50. doi: 10.1111/j.1572-0241.2006.00390.x. PMID 16454841
- BACKGROUNDDik VK, Gralnek IM, Segol O, Suissa A, Belderbos TD, Moons LM, Segev M, Domanov S, Rex DK, Siersema PD. Multicenter, randomized, tandem evaluation of EndoRings colonoscopy--results of the CLEVER study. Endoscopy. 2015 Dec;47(12):1151-8. doi: 10.1055/s-0034-1392421. Epub 2015 Jul 28. PMID 26220283