Clinical trial · Interventional
Adaptated Physical Activity During Chemotherapy: Evaluation of the Psychological, Physiological and Biological Impact
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Insufficient recruitment
Summary
Brief summary (as posted)
Although treatments significantly increase the life expectancy of cancer patients, their quality of life is more or less reduced. The development of supportive care, such as physical activity, is one of the tools that should be promoted to maintain quality of life and reduce treatment side effects, including fatigue. This study was developed to understand the different biopsychosocial effects of a physical activity program carried out with patients suffering from various types of cancers, and to facilitate and improve the implementation of this type of activity in health care facilities. Study randomized, controlled, cross-over intervention evaluating a 12-week supervised and adapted physical activity program. Participants were assigned to one of two groups: Group A which first follows a 12-week physical activity program, then undergoes usual care for 12 additional weeks, or Group B, which continues usual care for 12 weeks (control group) and then starts the physical activity program for 12 additional weeks. Quality of life (with questionnaires for 2 groups) , well-being, fatigue, physical capacity, leptin concentration, goal setting and level of physical activity are evaluated during this protocol. By understanding the multidimensional effects of a physical activity program for various cancer types, depending on the time of proposing the program, by evaluating the correlations among all these variables, and by evaluating long-term effects, the IPCAPA study contributes to identifying the physical activity program which will be effective, viable and feasible for all patients undergoing chemotherapy, whatever the type of cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 6-minute walk test) every 6 weeks (T0, T1, T2, T3 and T4) | Other | — | UNRESOLVED |
| leptin level with a blood test every 12 weeks (T0, T2 and T4) | Other | — | UNRESOLVED |
| questionnaires every 6 weeks (T0, T1, T2, T3 and T4) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Immediate adaptated physical activity (Group A)
- description
- Group A began a physical activity program for 12 consecutive weeks from inclusion in the protocol, then underwent the usual care for 12 additional weeks. Then to complete five evaluations with several questionnaires, and 6-minute walk test every 6 weeks (T0, T1, T2, T3 and T4) and leptin level with a blood test every 12 weeks (T0, T2 and T4).
- interventionNames
- Other: questionnaires every 6 weeks (T0, T1, T2, T3 and T4)
- Other: 6-minute walk test) every 6 weeks (T0, T1, T2, T3 and T4)
- Other: leptin level with a blood test every 12 weeks (T0, T2 and T4)
- type
- OTHER
- label
- Without immediate adaptated physical activity (Group B)
- description
- Group B followed the usual care for 12 weeks then started the physical activity program for 12 additional weeks. Then to complete five evaluations with several questionnaires, and 6-minute walk test every 6 weeks (T0, T1, T2, T3 and T4) and leptin level with a blood test every 12 weeks (T0, T2 and T4).
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient aged 18 years or more, * Performance status (WHO) ≤ 2 * Ability to participate in the IPCAPA program and medical certification of no contraindications to exercise * Availability and willingness to participate in the IPCAPA study for the duration of the protocol * Affiliated to a social security system * Signed informed consent. Exclusion Criteria: * Pregnant or breastfeeding woman. * Woman with childbirth ability without effective contraception. * Patient in emergency situations, adult subject to a measure of legal protection (major trusteeship, guardianship or ward of court), or unable to consent. * Inability to undergo medical monitoring of the trial for geographical, social or psychological reasons. * Inability to practice physical activity. * Planned surgery within 24 weeks of inclusion.
References
Publications (0)
Data not yet available