Clinical trial · Interventional
SymptomCare@Home: Deconstructing an Effective Symptom Management Intervention
SymptomCare@Home (SCH): Deconstructing an Effective, Technology-assisted, Symptom Management Intervention
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This project will determine the most important and cost effective components of SymptomCare@Home, a new approach to cancer chemotherapy symptom care that has been shown to reduce problematic symptoms through automated daily monitoring, self-management coaching, and oncology team follow-up care using decisional support for patients at home when their symptoms are most likely at their worse. Once the key parts of the intervention and its cost effectiveness are known, it can be moved into everyday cancer care.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| AT | Behavioral | — | UNRESOLVED |
| DSS | Behavioral | — | UNRESOLVED |
| Nurse Practitioner | Behavioral | — | UNRESOLVED |
| SCC | Behavioral | — | UNRESOLVED |
| Symptom Severity | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- type
- ACTIVE_COMPARATOR
- label
- Group 1 SCC/SSR
- description
- This arm includes self-care coaching (SCC) message during daily self-reported symptom severity report (SSR) calls to the automated system.
- interventionNames
- Behavioral: SCC
- Behavioral: Symptom Severity
- type
- ACTIVE_COMPARATOR
- label
- Group 2 NP/SSR
- description
- Alert reports are generated during the patient's daily symptom severity monitoring call if alert thresholds are reached. These alerts are monitored and follow-up care is given by a nurse practitioner.
- interventionNames
- Behavioral: Nurse Practitioner
- Behavioral: Symptom Severity
- type
- ACTIVE_COMPARATOR
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histological diagnosis of cancer * Life expectance of at least three months * Beginning a new course of chemotherapy that is planned for a minimum of three cycles * English speaking * Daily access to a telephone * Cognitively capable to use the phone unassisted as verified by study staff at recruitment * Receiving care under the direction of one of the designated provider teams at Huntsman Cancer Institute (SLC, UT) or Grady Cancer Institute (Atlanta, GA). Exclusion Criteria: * Receiving concurrent radiation therapy * Exclusively receiving biotherapy
References
Publications (1)
- DERIVEDMooney K, Gullatte M, Iacob E, Alekhina N, Nicholson B, Sloss EA, Lloyd J, Moraitis AM, Donaldson G. Essential Components of an Electronic Patient-Reported Symptom Monitoring and Management System: A Randomized Clinical Trial. JAMA Netw Open. 2024 Sep 3;7(9):e2433153. doi: 10.1001/jamanetworkopen.2024.33153. PMID 39269704