Clinical trial · Observational
The Added Value of Hybrid Functional Anatomical Imaging PET-CT and SPECT-CT in Patients Treated With Y-90 SIRT for Liver Malignancies
The Added Value of Hybrid Functional Anatomical Imaging PET-CT and SPECT-CT in Patients Treated With Yttrium-90 SIRT for Liver
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients cohort is composed of 50 consecutive patients both male and female with hepatic malignancies, refered to our nuclear medicine department in the process of radioembolization between January 2010- August 2015. 26 of the patients were examined with Tc99-MAA and SPECT-CT and 24 patients were examined with Tc99-MAA , SPECT-CT and PET-CT. Our study protocol was as follows: 1. Collection of anamnestic data 2. Calculation of liver tumor volume with quantification software 3. Evaluation of the liver tumor involvement 4. Evaluation of liver to lung shunt 5. Calculation dose of SIRTEX 6. Y90 imaging 7. Follow Up
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Primary Liver Tumor, Metastatic Liver | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tc99-MAA | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Tc99-MAA and SPECT-CT
- description
- 26 of the patients were examined with Tc99-MAA and SPECT-C
- interventionNames
- Other: Tc99-MAA
- label
- Tc99-MAA , SPECT-CT and PET-CT
- description
- 24 patients were examined with Tc99-MAA , SPECT-CT and PET-CT.
- interventionNames
- Other: Tc99-MAA
Primary outcomes (1)
- measure
- Visual assesment of Tc-99m-MAA in liver lesions compared to visual assesment of Y-90 sirtex.
- timeFrame
- one year
- description
- Undestanding the role of Tc-99- MAA in the prediction of Y90 sirt uptake in liver lesions by visual assesment with PET-CT and SPECT-CT imaging
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 1\. Age ≥ 18. 2. Patients with malignancy of the liver (metastasis or primary tumor) who were treated with Y90 SIRT and were refered to the nuclear medicine department for a PET-CT. Exclusion Criteria: * 1\. Age \< 18. 2. Pregnant woman 3. Children and legally incompetent.
References
Publications (0)
Data not yet available