Clinical trial · Interventional
Dietary Prevention of Photodamage in Skin With Grapes
Dietary Prevention of Photodamage in Skin With Grapes: A Human Clinical Study
NCT02760160CI-TRIAL-00037520completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To assess the effect of orally administered grape powder on the sunburn reaction in humans.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non-melanoma Skin Cancer | Skin Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Reconstituted grape powder | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Reconstituted grape powder
- description
- Open grape powder pouch and pour contents into volumetric measuring device. Add approximately 180 mL of water to container with grape powder. Stir for a minimum of 30 seconds and ingest.
- interventionNames
- Other: Reconstituted grape powder
Primary outcomes (1)
- measure
- Number of subjects reporting protective effect against sunburn response to UVG and/or UVA1 following administration of dietary grape powder.
- timeFrame
- 2 weeks
- description
- Assessment will be quantified by evaluation of a person's minimal erythema dose (MED), the smallest amount of ultraviolet (UV) required to achieve a sunburn response. 6 small areas of skin (2 inches by 2 inches) on the inner part of a person's arm will be exposed to 6 separate but increasing doses of UV. 24 hours after UV treatment, the area that received the smallest dose of UV and has a visible area of redness will be marked and the respective UV dose will be considered the MED. A desirable outcome would be if an individual's MED goes up after 2 weeks of grape treatment.
Secondary outcomes (11)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Patient age 18 and older * Patient able to understand requirements of the study and risks involved * Patient able to sign a consent form Exclusion Criteria: * Patients Fitzpatrick IV-VI * A recent history of vitiligo, melasma, and other disorders of pigmentation with the exception of post inflammatory hyperpigmentation * A known history of photosensitivity disorders * A known history of melanoma or non-melanoma skin cancers * Those planning on going to the tanning parlors * Using any of the photosensitizing medication * A woman who is lactating, pregnant, or planning to become pregnant * Patient planning on exposing the irradiated or control areas to the sun
References
Publications (0)
Data not yet available
No reference posted for this study.