Clinical trial · Observational
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being
NCT02749474CI-TRIAL-00077823CANCRPREGREGunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to follow the treatment options offered to pregnant women diagnosed with cancer and study the impact that their treatment or delay of treatment has on their own health and that of their children.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pregnancy, Cancer, Cancer in Pregnancy, Gestational Breast Cancer, Pregnancy Related | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Pregnant women diagnosed with cancer
- description
- Any pregnant woman diagnosed with any cancer within 6 weeks prior to their last menstrual period, or up to 6 months after the end of their pregnancy can be enrolled.
Primary outcomes (1)
- measure
- Neonatal Developmental Quotient
- timeFrame
- Yearly from 3 months to 12 years of age
- description
- Pediatrician asked to assess developmental age compared to chronological age, ie developmental quotient
Secondary outcomes (1)
- measure
- Congenital Malformations
- timeFrame
- From birth to 5 years of age
- description
- Incidence of children in registry diagnosed with birth defects after a pregnancy complicated by a cancer diagnosis.
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * Any pregnant woman diagnosed with cancer within 6 weeks before her last menstrual period or 6 months after her end of pregnancy either by delivery or miscarriage. Exclusion Criteria: * Women diagnosed with cancer more than 6 months after the end of a pregnancy.
References
Publications (29)
- BACKGROUNDCardonick E. Pregnancy-associated breast cancer: optimal treatment options. Int J Womens Health. 2014 Nov 4;6:935-43. doi: 10.2147/IJWH.S52381. eCollection 2014. PMID 25395871
- BACKGROUNDCardonick E. Treatment of maternal cancer and fetal development. Lancet Oncol. 2012 Mar;13(3):218-20. doi: 10.1016/S1470-2045(11)70408-9. Epub 2012 Feb 10. No abstract available. PMID 22326923
- BACKGROUNDCardonick E. Cancer occurs in approximately 1 per 1,000 pregnancies. Oncology (Williston Park). 2008 Jul;22(8 Suppl Nurse Ed):22-3. No abstract available. PMID 19856567
- BACKGROUNDCardonick E, Iacobucci A. Use of chemotherapy during human pregnancy. Lancet Oncol. 2004 May;5(5):283-91. doi: 10.1016/S1470-2045(04)01466-4. PMID 15120665
- BACKGROUNDLevy C, Pereira L, Dardarian T, Cardonick E. Solid pseudopapillary pancreatic tumor in pregnancy. A case report. J Reprod Med. 2004 Jan;49(1):61-4. PMID 14976799
- BACKGROUNDBerghella V, Broth RE, Chapman AE, Cardonick E. Metastatic unknown primary tumor presenting in pregnancy as multiple cerebral infarcts. Obstet Gynecol. 2003 May;101(5 Pt 2):1060-2. doi: 10.1016/s0029-7844(02)02333-5. PMID 12738101
- BACKGROUNDPartridge AH, Pagani O, Abulkhair O, Aebi S, Amant F, Azim HA Jr, Costa A, Delaloge S, Freilich G, Gentilini OD, Harbeck N, Kelly CM, Loibl S, Meirow D, Peccatori F, Kaufmann B, Cardoso F. First international consensus guidelines for breast cancer in young women (BCY1). Breast. 2014 Jun;23(3):209-20. doi: 10.1016/j.breast.2014.03.011. Epub 2014 Apr 24. PMID 24767882
- BACKGROUNDVandenbroucke T, Amant F. Development of children born to mothers with cancer during pregnancy: comparing in utero chemotherapy-exposed children with nonexposed controls. Am J Obstet Gynecol. 2015 Jun;212(6):830-1. doi: 10.1016/j.ajog.2015.01.035. Epub 2015 Jan 28. No abstract available.