Clinical trial · Observational
Paravertebral Block (PVB) Combined Pectoral Musculature Blocks for Modified Radical Mastectomy (MRM)
Comparisons the Analgesia of Paravertebral Block Combined With Thoracic Wall Block Versus Paravertebral Block Alone for Modified Radical Mastectomy in Breast Cancer
NCT02747992CI-TRIAL-00021889completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Previous studies have shown that PVB reduces pain and postoperative nausea and vomiting after breast cancer surgery when used in addition to general anesthesia or sedation. However, major breast cancer surgery involves areas beyond the breast tissue, such as pectoral musculature.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mastectomy, Modified Radical | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- PECS 0
- description
- receiving paravertebral block
- label
- PECS 1
- description
- receiving paravertebral block and blocks targeting pectoral musculature
Primary outcomes (1)
- measure
- intraoperative sedation requirement
- timeFrame
- during operation
- description
- target controlled infusion (TCI) propofol driven by the Schnider model in effect site control titrated to reach conscious sedation defined as Observer Assessment of Alertness/Sedation score of 2 to 3
Secondary outcomes (3)
- measure
- time to first request of analgesics
- timeFrame
- postoperative 12 hours
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * The American Society of Anesthesiologists (ASA) Physical Status classification I to III * 20 - 75 years of age * female gender Exclusion Criteria: * body mass index (BMI) ≥ 35 kg/m2 * modified radical mastectomy not performed by the single surgeon (Ben Long Yu) * anesthesia not performed by the single anesthesiologist (Nai Liang Li)
References
Publications (0)
Data not yet available
No reference posted for this study.