Clinical trial · Interventional
Inferior Alveolar Nerve Block for Intraoperative Analgesia for Maxillofacial Cancer Surgery - RCT
Inferior Alveolar Nerve Block for Intraoperative Analgesia for Maxillofacial Cancer Surgery Requiring Unilateral Mandibular Resection-A Randomized Controlled Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Mandibular resection which is an important component of maxillofacial cancer surgery is an extremely painful procedure associated with severe sympathetic response needing high doses of opioids. Inferior alveolar nerve block is a common nerve block used by dentists for mandibular dental extractions. The aim of this trial is to study the effect of this block for intraoperative analgesia in maxillofacial cancer surgeries requiring unilateral mandibular resection.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mandibular Neoplasms | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| inferior alveolar nerve block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Nerve block
- description
- This arm will receive inferior alveolar nerve block
- interventionNames
- Procedure: inferior alveolar nerve block
- type
- NO_INTERVENTION
- label
- control
- description
- Control arm will not receive inferior alveolar block
Primary outcomes (1)
- measure
- IV fentanyl requirement during primary tumour removal
- timeFrame
- From start to finish ofprimary tumour removal procedure
- description
- The total IV fentanyl dose required during primary tumour removal will be noted
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * All patients between the age of 18 and 75 yrs classified as ASA I and II physical status requiring maxillofacial cancer surgery requiring unilateral mandibular resection and unilateral neck dissection Exclusion Criteria: * \- surgery involving upper alveolar / maxillary resection * patients with BMI below 18kg/m2 and above 30kg/m2 * allergy to local anaesthetic agent * Inability to give inferior alveolar nerve block due to any cause e.g. restricted mouth opening, obscured landmark or infection at site * pregnant women * patients unable to give valid consent e.g. patients with learning difficulties * patients on medications for hypertension * patients with preoperative pain requiring regular pain medications * uncontrolled haemodynamic status e.g. baseline arterial blood pressure above 160 /90 and baseline HR above 100 /min
References
Publications (0)
Data not yet available