Clinical trial · Observational
Study on Cannabinoid Receptor Expression in Gastrointestinal Diseases
Expression of G Protein-coupled Receptors and Ligands in Inflammatory Bowel Diseases and Colon Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to investigate phospholipid ligands and their receptors in inflammatory bowel diseases and colon cancer. Several new species of lipids have been recently discovered which are able to transmit information to cancer cells in the large intestine. The lipids and their responsive receptors build an axis that is thought to influence the development of inflammation and cancer.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Crohn's Disease | — | UNRESOLVED | — |
| Ulcerative Colitis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (4)
- label
- UC group
- description
- Patients with ulcerative colitis (active or remission)
- label
- CD group
- description
- Patients with Crohn's disease (active or remission)
- label
- Colon cancer group
- description
- Patients with colon cancer or metastasis
- label
- control group
- description
- healthy individuals
Primary outcomes (1)
- measure
- Analysis of cannabinoid receptors in blood leukocytes and biopsies from patients with IBD and colon cancer
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of Ulcerative colitis (active/remission) * or Crohn's disease (active/remission) * or Colon cancer (or metastasis) Exclusion Criteria: * unable to give informed consent * pregnancy * intermittent illness or comorbidity during Crohn/Ulcerative colitis
References
Publications (0)
Data not yet available