Clinical trial · Interventional
IORT Followed by CCRT or SBRT for Locally Advanced Pancreatic Cancer
Intraoperative Radiotherapy(IORT) Followed by Concurrent Chemoradiotherapy(CCRT) or Stereotactic Radiotherapy(SBRT) for Locally Advanced Pancreatic Cancer
NCT02734680CI-TRIAL-00026912IFCSLAPCunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to find the best model of combination of intraoperative radiotherapy(IORT) and postoperative radiochemotherapy for pancreatic cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Concurrent chemoradiotherapy(CCRT) | Radiation | — | UNRESOLVED |
| S-1 | Drug | — | UNRESOLVED |
| Stereotactic Radiotherapy(SBRT) | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Concurrent chemoradiotherapy(CCRT) Group
- description
- Concurrent chemoradiotherapy(CCRT) (Total dose: 46 Gy; Single dose: 2 Gy; Frequency: 23; Gemcitabine(GEM), 300 mg/m2 weekly); Followed by taking S-1 orally (40 mg/m2, bid on Day 1-28, Q42d)
- interventionNames
- Radiation: Concurrent chemoradiotherapy(CCRT)
- Drug: S-1
- type
- EXPERIMENTAL
- label
- Stereotactic Radiotherapy(SBRT) Group
- description
- Stereotactic Radiotherapy(SBRT) (Total dose: 45 Gy; Single dose: 3 Gy; Frequency: 15) Followed by taking S-1 orally (40 mg/m2, bid on Day 1-28, Q42d)
- interventionNames
- Radiation: Stereotactic Radiotherapy(SBRT)
- Drug: S-1
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosed as locally advanced pancreatic cancer. * Cannot be treated by surgical resection. Exclusion Criteria: * Treated by chemotherapy or radiotherapy before. * With distant organ metastasis. * Cannot tolerate surgery (Intraoperative radiotherapy)
References
Publications (0)
Data not yet available
No reference posted for this study.