Clinical trial · Observational
Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease
Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease - DYSCOLIC
NCT02726243CI-TRIAL-00074404DYSCOLICcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Build a collection of fecal microbiota in order to determine the characteristics of gut microbiota associated with colorectal cancer in Inflammatory bowel disease (IBD).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Inflammatory Bowel Disease | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (8)
- label
- IBD without CRC
- label
- IBD with CRC
- label
- IBD with dysplasia
- label
- non IBD without CRC
- label
- non IBD with CRC
- label
- IBD-PSC without CRC
- label
- IBD-PSC with CRC
- label
- IBD-PSC with dysplasia or healthy subjects
- description
- IBD-PSC with dysplasia or healthy subjects for whom a colonoscopy is scheduled
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with the capacity to give informed consent. * Age ≥ 18 years. * A patient with IBD (Crohn's disease or ulcerative colitis) or healthy subject having a screening colonoscopy scheduled. * Diagnosis of pathologies in question established or confirmed in any of the services involved in the study and according to international diagnostic criteria (Consensus ECCO). * Patient follow-up in one of the services involved in the study Exclusion Criteria: * trusteeship, guardianship or safeguard justice. * Subject does not speak French. * Subject unable to answer questions or to speak. * Previous history of colonic resection * Taking antibiotics within 8 weeks preceding the stool sample Temporary exclusion criterium) * Taking a bowel preparation for colonoscopy within 6 weeks before the stool sample (temporary exclusion criterium). Sampling is possible before bowel preparation or on the first stool after starting the bowel preparation. * Ostomy at the time of sampling * Current treatment by radiotherapy, chemotherapy
References
Publications (1)
- RESULTLavelle A, Nancey S, Reimund JM, Laharie D, Marteau P, Treton X, Allez M, Roblin X, Malamut G, Oeuvray C, Rolhion N, Dray X, Rainteau D, Lamaziere A, Gauliard E, Kirchgesner J, Beaugerie L, Seksik P, Peyrin-Biroulet L, Sokol H. Fecal microbiota and bile acids in IBD patients undergoing screening for colorectal cancer. Gut Microbes. 2022 Jan-Dec;14(1):2078620. doi: 10.1080/19490976.2022.2078620. PMID 35638103