Clinical trial · Interventional
Targeted Internal Radiation Therapy in Advanced HCC Patients.
A Randomized Controlled Prospective Study of Targeted Internal Radiation Therapy in Patients With Advanced Hepatocellular Carcinoma.
NCT02724267CI-TRIAL-00021575completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to evaluate the 131I-chTNT-1/B treatment effect and safety of individual therapy using randomized controlled study, in order to acquire the evidence of evidence-based medicine and create a new program of targeted internal radiation therapy in advanced HCC patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Hepatocellular Carcinoma | Hepatocellular Carcinoma | CURATED_BROADER | 0.78 |
| Internal Radiation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 131I-chTNT-1/B | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- transcatheter arterial chemoembolization
- description
- Patients will be treated with TACE only.
- interventionNames
- Biological: 131I-chTNT-1/B
- type
- EXPERIMENTAL
- label
- internal radiation group
- description
- Patients will be treated with TACE combined with internal radiation.
- interventionNames
- Biological: 131I-chTNT-1/B
Primary outcomes (1)
- measure
- Overall Survival
- timeFrame
- 3 years
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Via clinical diagnosis and confirm it is advanced hepatocellular carcinoma 2. mRECIST estimation: necrosis region in HCC 3. Negative iodine allergy test 4. Liver function ：Child-Pugh A/B Exclusion Criteria: 1. reject to attend； 2. impossible to come to our hospital for physical examination regularly. 3. Blood clotting function hindrance; 4, Patients with apparent cardiac, pulmonary, cerebral and renal dysfunction,which may affect the treatment of liver cancer.
References
Publications (0)
Data not yet available
No reference posted for this study.