Clinical trial · Interventional
18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR
Reproducibility of 18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR
NCT02717572CI-TRIAL-00037957completedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In the current study, the investigators plan to expand the knowledge of Positron Emission Tomography/Magnetic Resonance (PET/MR) reliability by assessing the repeatability of fludeoxyglucose (FDG) standardized uptake values (SUV) measurements, as well as apparent diffusion coefficients (ADC) measurements, in a broad population of patients with malignant solid tumors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumor, Adult | Adult Solid Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Computerized Tomography | Device | — | UNRESOLVED |
| Fludeoxyglucose F 18 | Radiation | — | UNRESOLVED |
| Magnetic Resonance Imaging | Device | — | UNRESOLVED |
| Positron Emission Tomography | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- FDG-PET/CT and FDG-PET/MR
- description
- * 10 mCI fludeoxyglucose IV bolus approximately 60 minutes before first PET/CT * Immediately following PET/CT scan, the participant will be moved to PET/MR scanner * The scans will take place at baseline and also one more time point between Day 1 and Day 7. There needs to be at least 24 hours between the baseline and repeat imaging
- interventionNames
- Radiation: Fludeoxyglucose F 18
- Device: Positron Emission Tomography
- Device: Computerized Tomography
- Device: Magnetic Resonance Imaging
Primary outcomes (4)
- measure
- Variability of repeated quantitative measures of FDG uptake as measured by SUVmax
- timeFrame
- Completion of study (up to Day 7)
- description
- -SUVmax is the maximum standardized uptake value (SUV) of the area of showing metabolic activity and this is used to show response
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with histologically confirmed malignant solid tumors (local or metastatic, newly diagnosed or recurrent disease). * Patient must have at least one lesion measuring ≥ 2.0 cm. * 18 years of age or older. * Ability to provide informed consent. Exclusion Criteria: * Cancer therapy within 30 days of baseline imaging. * Uncontrolled intercurrent illness including, but not limited to active infections. * Patients with insulin-dependent diabetes. * Patients with metal devices in the body including, but not limited to metallic joint prostheses, artificial heart valves, pacemakers, and cochlear implants. * Patients who are pregnant or nursing. * Inability to tolerate 60 minutes of PET imaging. * Inability to comply with study procedures.
References
Publications (0)
Data not yet available
No reference posted for this study.