Clinical trial · Interventional
Laparoscopic-assisted Total Gastrectomy Versus Open Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
Laparoscopic-assisted Total Gastrectomy Versus Open Total Gastrectomy With Spleen-preserving Splenic Hilum Lymph Nodes Dissection for Advanced Proximal Gastric Cancer: A Randomized Controlled Trial
NCT02711033CI-TRIAL-00026893unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates the safety and feasibility of laparoscopic-assisted total gastrectomy with spleen-preserving splenic hilum lymph node dissection for proximal advanced gastric cancer and compares the early results of this procedure with open total gastrectomy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Splenic Hilum Lymph Nodes Dissection | — | UNRESOLVED | — |
| Total Gastrectomy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic-assisted total gastrectomy | Procedure | — | UNRESOLVED |
| Open total gastrectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Laparoscopic-assisted total gastrectomy
- description
- Patients including in the laparoscopic-assisted total gastrectomy (LATG) group will undergo LATG with spleen-preserving splenic hilum lymph nodes dissection.
- interventionNames
- Procedure: Laparoscopic-assisted total gastrectomy
- type
- ACTIVE_COMPARATOR
- label
- Open total gastrectomy
- description
- Patients who are included in the open total gastrectomy (OTG) group will OTG with spleen-preserving splenic hilum lymph nodes dissection.
- interventionNames
- Procedure: Open total gastrectomy
Primary outcomes (1)
- measure
- Early complication rate
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with advanced proximal gastric cancer （T2-T4a,N0-N3,M0） * Informed consent * Eastern Cooperative Oncology Group (ECOG): 0 ot 1 * American Society of Anesthesiologists （ASA） score: Ⅰto Ⅲ Exclusion Criteria: * Pregnancy or female in suckling period * Contraindication to general anesthesia (severe cardiac and/or pulmonary disease) * Severe mental disease * Emergency operation due to complication (bleeding, perforation or obstruction) caused by primary tumor * Body mass index (BMI) \> 30 kg/m2
References
Publications (0)
Data not yet available
No reference posted for this study.