Clinical trial · Interventional
Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests
Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests in Patients Undergoing Endoscopic Endonasal Transsphenoidal Surgery of Pituitary Gland
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will compare the effects of sevoflurane, desflurane and total intravenous anaesthesia on pulmonary function tests in patients undergoing endoscopic endonasal transsphenoidal surgery of pituitary gland. Participants will be divided into three equal groups. The first group will receive sevoflurane, second grup will receive desflurane and third grup will receive total intravenous anaesthesia. Investigators are also going to evaluate blood gas analysis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pituitary Adenoma | Pituitary Neuroendocrine Tumor | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Desflurane | Drug | — | UNRESOLVED |
| Propofol | Drug | — | UNRESOLVED |
| Sevoflurane | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Sevoflurane
- description
- 1-1.5 minimum alveolar concentration (MAC), inhalation route, during operation
- interventionNames
- Drug: Sevoflurane
- type
- ACTIVE_COMPARATOR
- label
- Desflurane
- description
- 1-1.5 minimum alveolar concentration (MAC), inhalation route, during operation
- interventionNames
- Drug: Desflurane
- type
- ACTIVE_COMPARATOR
- label
- Propofol
- description
- 6-10 mg/kg/h, iv infusion, during operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * American Society of Anesthesiologists (ASA) score I-II patients Exclusion Criteria: * Significant cardiopulmonary disease, * Diagnosed obstructive or restrictive pulmonary disease, * Patients with chest wall deformities, liver or kidney failure, * Postoperative lack of cooperation
References
Publications (0)
Data not yet available