Clinical trial · Observational
Prospective Study of Patients With Rheumatoid Arthritis After the Age of 65
Prospective Study of Evolution of Rheumatoid Arthritis After 65 Years Old
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study suspended due to lack of PI to handle it
Summary
Brief summary (as posted)
Rheumatoid arthritis (RA) is associated with a higher prevalence of infections, malignancies, osteoporotic fractures and cardiovascular diseases. Few data are available regarding the prevalence and severity of these comorbidities in elderly RA patients. The purpose of this study is to determine the effect of age on prevalence and severity of comorbidities in RA.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rheumatoid Arthritis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Rheumatoid arthritis >65 years old
- label
- Rheumatoid arthritis <50 years old
Primary outcomes (4)
- measure
- Number of severe infections
- timeFrame
- 5 years
- description
- Occurrence of severe infection requiring hospitalization or varicella-zoster virus
- measure
- Number of cancers
- timeFrame
- 5 years
- description
- Occurrence of solid cancer or hemopathy
- measure
- Number of cardiovascular diseases
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of Rheumatoid arthritis according to American College of Rheumatology (ACR) /Eular 2010 criteria or American College of Rheumatalogy 1987 criteria * Age \>65 years or patients between 18 and 50 years matched for sex and disease duration with the group of elderly patients (control group) Exclusion Criteria: * Patients who do not understand rules and implications of the study
References
Publications (2)
- BACKGROUNDSoubrier M, Tatar Z, Couderc M, Mathieu S, Dubost JJ. Rheumatoid arthritis in the elderly in the era of tight control. Drugs Aging. 2013 Nov;30(11):863-9. doi: 10.1007/s40266-013-0122-8. PMID 24105334
- BACKGROUNDWiddifield J, Bernatsky S, Paterson JM, Gunraj N, Thorne JC, Pope J, Cividino A, Bombardier C. Serious infections in a population-based cohort of 86,039 seniors with rheumatoid arthritis. Arthritis Care Res (Hoboken). 2013 Mar;65(3):353-61. doi: 10.1002/acr.21812. PMID 22833532