Clinical trial · Interventional
Self-sampling for Non-participants in an Organised Cervical Cancer Screening Programme
A Three-armed Randomised Controlled Trial of Non-participants in an Organised Cervical Cancer Screening Programme
NCT02680262CI-TRIAL-00035301CHOiCEcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The trial will evaluate the effect on participation in organised screening programme of a human papilloma virus (HPV) self-sampling kit directly mailed home or mailed on demand compared with the standard second reminder for regular screening.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| HPV self-sampling kit mailed directly | Behavioral | — | UNRESOLVED |
| HPV self-sampling kit on demand | Behavioral | — | UNRESOLVED |
| Second reminder | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Intervention group 1
- description
- HPV self-sampling kit mailed directly
- interventionNames
- Behavioral: HPV self-sampling kit mailed directly
- type
- EXPERIMENTAL
- label
- Intervention group 2
- description
- HPV self-sampling kit on demand
- interventionNames
- Behavioral: HPV self-sampling kit on demand
- type
- EXPERIMENTAL
- label
- Intervention group 3
- description
- second reminder
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 64 Years
Show eligibility criteria text
Inclusion Criteria: * Women resident in the Central Denmark Region who have not participate in cervical cancer screening after an invitation and one reminder Exclusion Criteria: * Women younger than 30 years are not included due to the lower specificity of HPV DNA tests in younger women
References
Publications (3)
- DERIVEDTranberg M, Bech BH, Blaakaer J, Jensen JS, Svanholm H, Andersen B. HPV self-sampling in cervical cancer screening: the effect of different invitation strategies in various socioeconomic groups - a randomized controlled trial. Clin Epidemiol. 2018 Aug 23;10:1027-1036. doi: 10.2147/CLEP.S164826. eCollection 2018. PMID 30197540
- DERIVEDTranberg M, Bech BH, Blaakaer J, Jensen JS, Svanholm H, Andersen B. Preventing cervical cancer using HPV self-sampling: direct mailing of test-kits increases screening participation more than timely opt-in procedures - a randomized controlled trial. BMC Cancer. 2018 Mar 9;18(1):273. doi: 10.1186/s12885-018-4165-4. PMID 29523108
- DERIVEDTranberg M, Bech BH, Blaakaer J, Jensen JS, Svanholm H, Andersen B. Study protocol of the CHOiCE trial: a three-armed, randomized, controlled trial of home-based HPV self-sampling for non-participants in an organized cervical cancer screening program. BMC Cancer. 2016 Nov 3;16(1):835. doi: 10.1186/s12885-016-2859-z. PMID 27809810