Clinical trial · Interventional
Preoperative HIIT in Elderly Cancer Patients
A Randomised Control Trial to Assess Efficacy of Preoperative High Intensity Interval Training in Elderly Patients Scheduled for Oncological Abdominal Surgery
NCT02671617CI-TRIAL-00034879eHIITCacompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized control trial will determine the effect of short term high intensity interval training (HIIT) on physical fitness, in an elderly patient group with active cancer, prior to surgical resection. Half of the recruited patients will act as a control group and the other half will undergo a HIIT protocol.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| High intensity interval training (HIIT) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control
- description
- Control: This group of patients will receive 'current best practice' as per UK NHS recommendations for their specific cancer management prior to surgery.
- type
- EXPERIMENTAL
- label
- High intensity interval training
- description
- Exercise: Participants in this group will attend 3-4 times per week to complete HIIT training during the period from diagnosis to surgery. High intensity interval training (HIIT)
- interventionNames
- Other: High intensity interval training (HIIT)
Primary outcomes (1)
- measure
- VO2AT (VO2 at anaerobic threshold)
- timeFrame
- Baseline and 4 weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Aged over 65 years (no upper age limit). * Histologically proven, radiologically or direct visualisation leading to high clinical suspicion of cancer. * Sufficient mobility to be able to exercise on a static exercise bike. * Ability to give informed consent. * Ability to travel to RDH to complete the HIIT sessions (may also rely upon dependents/relatives to provide transport). Exclusion Criteria: * Adjuvant systemic chemotherapy / radiotherapy treatment for this cancer. Participants with a significant past medical history of: * Myocardial infarction (within last 6 months) * Unstable Angina * Heart failure (NYHA class III/IV) * Uncontrolled Hypertension (BP\>160/100) * Previous stroke/TIA * Severe respiratory disease inc. known pulmonary hypertension(\>25 mmHg), Forced Expiratory Volume in 1 second \<1.5l. * Brittle asthma / exercise induced asthma * Known cerebral aneurysm. * Inclusion in a recent (within 3 months) study which included any form of exercise, taking a drug or ionising radiation.
References
Publications (0)
Data not yet available
No reference posted for this study.