Clinical trial · Interventional
Computerized Cognitive Retraining in Improving Cognitive Function in Breast Cancer Survivors
Computerized Cognitive Retraining in Breast Cancer Survivors
NCT02662335CI-TRIAL-00030800completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized clinical trial studies computerized cognitive retraining in improving cognitive function in breast cancer survivors. Cancer-related cognitive deficits, such as thinking and memory issues, are common among breast cancer survivors. The severity of these cognitive deficits is associated with a significant negative impact on daily function and quality of life. A computerized cognitive retraining method may help researchers find ways to improve cognitive function and quality of life in breast cancer survivors.
Conditions
Conditions (9)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Survivor | — | UNRESOLVED | — |
| Stage 0 Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IA Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IB Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIA Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIB Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIIA Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIIB Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIIC Breast Cancer | Malignant Breast Neoplasm |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Computer-Assisted Cognitive Training | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
| Standard Follow-Up Care | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (computer-assisted cognitive training)
- description
- Patients complete a computerized working memory training program (Cogmed) over 35 minutes a day, 5 times a week for 6 weeks.
- interventionNames
- Other: Computer-Assisted Cognitive Training
- Other: Questionnaire Administration
- type
- ACTIVE_COMPARATOR
- label
- Arm II (wait-list)
- description
- Patients undergo standard follow-up care for 6 weeks. Following standard follow-up care, patients may complete Cogmed as in the Intervention Group in weeks 7-13.
- interventionNames
- Other: Questionnaire Administration
- Procedure: Standard Follow-Up Care
Primary outcomes (4)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Breast cancer (stage 0, I, II, III), 18 months to 5 years post oncologic therapies of surgery, chemotherapy, and/or radiation therapy (does not exclude current selective estrogen receptor modulators or aromatase inhibitors) * Able to read, write, and speak English * Mini Mental State Exam score greater than or equal to 19 * Have reliable internet and daily access to computer with audio/speakers * Agree to travel to the Seattle Cancer Care Alliance (SCCA) or University of Washington (UW) School of Nursing for 2-3 in person assessments over the 12-13 weeks of the study Exclusion Criteria: * History of multiple cancers * History of central nervous system (CNS) disease, CNS radiation, intrathecal therapy, or CNS surgery * History of traumatic brain injury * Neurologic disorders of stroke, encephalitis, dementia, epilepsy, Alzheimer's disease, Parkinson's disease * Self-report of learning disabilities * Substance addiction * Diagnosis of psychiatric disorders of psychosis, schizophrenia, or bipolar disorder * Mini mental state exam score less than 19 * Previous participation in cognitive training program * Visual impairments such as uncorrected vision or color blindness * Uncorrected hearing impairments * Self-report that they are not pregnant or planning to become pregnant in the next four months * Anticipate moving from the region in the next 4 months * Inability to use a mouse or computer keys to navigate around the computer screen
References
Publications (0)
Data not yet available
No reference posted for this study.