Clinical trial · Interventional
Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers
NCT02648178CI-TRIAL-00040710completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will test feasibility, in smokers with lung, head \& neck, and bladder cancers, that examines the effect of e-cigarette substitution, on measures of smoking-related toxicity and medical outcomes. The aim of the study is to determine the appeal of e-cigarettes compared to regular combustible cigarettes.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
| Cancer of Head and Neck | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Nicotine Dependence, Other Tobacco Product | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| HALO | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- HALO G6
- description
- HALO cigalike model
- interventionNames
- Device: HALO
- type
- ACTIVE_COMPARATOR
- label
- HALO Triton
- description
- HALO tank model
- interventionNames
- Device: HALO
Primary outcomes (2)
- measure
- Change in Daily Cigarette Smoking Given 10 or More E-cigarette Sessions in a Day
- timeFrame
- 12 Weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Histological or cytological diagnosis of lung, head \& neck, or bladder cancer within the past 5 years. 2. AJCC (American Joint Committee on Cancer) stages I-IV 3. Daily Smoking (at least 10 cigarettes per day for 10 years) and breath CO (carbon monoxide) greater than or equal to 9 ppm 4. Does not wish to quit smoking now (anyone wishing to quit smoking will be referred for smoking cessation counselling through the DHMC (Dartmouth Hitchcock Medical Center) program) 5. May be receiving anti-cancer agents 6. Age 18 or older 7. Fluent in English; 8. Patient must be capable and willing to provide informed written consent for study participation; 9. Able to participate in study visits Exclusion Criteria: 1. Cancer surgery planned in the next 9 weeks; 2. Treatment with radiation planned for the next 9 weeks, 3. Actively trying to quit smoking, or planning to in the next 30 days. (If a subject reports that they plan to quit smoking in the next 30 days, we will call them after the 30 days to see if they are still trying to quit.) 4. Any use of e-cigarettes in the past 30 days, 5. Pregnant or trying to get pregnant.
References
Publications (0)
Data not yet available
No reference posted for this study.