Clinical trial · Observational
Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature. The condition can be difficult to separate from adipositas in general. Screening for hypercortisolism in adults has been easier the last years, because we can measure free cortisol in saliva samples at late night. In children we still dont have reference ranges for saliva cortisol in children, so the screening is still troublesome, based on Collection of 24-hour urine.The meaning of this study is to establish reference ranges for saliva cortisol, and evaluate in a cohort with adipose children if screening with saliva cortisol is sensitive and specific enough to be the New screening test for hypercortisolism in children too.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cushings Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Children refered to the obesity clinic | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Children refered to the obesity clinic.
- description
- All children refered to the obesity clinic for examination and optionally treatment are invited.
- interventionNames
- Other: Children refered to the obesity clinic
Primary outcomes (2)
- measure
- Number of patients with positive saliva cortisol measurement, not having Cushings syndrome.
- timeFrame
- 2 years
- description
- Number of patients
- measure
- Number of patients With negative saliva cortisol measurement , having Cushings syndrome.
- timeFrame
- 2 years
- description
- Number of patients
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 4 Years
- Maximum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria:Children aged 4-16 years. Healthy population from selected kindergarten and Schools, and patients refered to the obesity clinic Haukeland University Hospital, for examination and optionally treatment. \- Exclusion Criteria:Use of any kind of steroids ( oral, liniments, inhalations etc) \-
References
Publications (0)
Data not yet available