Clinical trial · Observational
Perception of Cohesion Within a Relationship (Dyadic Adjustment) on the Quality of Life of Patients With Prostate Cancer With Gonadotropin-releasing Hormone.
Impact of the Perception of Cohesion Within a Relationship (Dyadic Adjustment) on the Quality of Life of Patients With Prostate Cancer With Gonadotropin-releasing Hormone (GnRH) Agonist Therapy Initiated by the Urologist in the Routine Practice. Evaluation by the Patient and the Partner.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The general hypothesis put forward in this study is that the degree of cohesion (agreement) in the relationship, or dyadic adjustment affects a patient's quality of life and clinical course during the first few critical months following diagnosis and the introduction of treatment. The level of cohesion in the relationship is certainly not the only parameter associated with changes in the quality of life. Other factors must also be investigated such as level of education, circumstances surrounding the diagnosis (new diagnosis or relapse), management (single therapy or adjuvant therapy), the level of physical activity, the patient's age and the presence of functional disorders, etc.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gonadotropin-releasing Hormone (GnRH) agonist therapy | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Prostate cancer patients
- interventionNames
- Drug: Gonadotropin-releasing Hormone (GnRH) agonist therapy
Primary outcomes (1)
- measure
- Change in quality of life of the patient.
- timeFrame
- Baseline and 6 months
- description
- Assessment of the dyadic adjustment and its impact on the quality of life of the patient through self-questionnaire by the patient and the partner
Secondary outcomes (4)
- measure
- Assessment of representations of illness
- timeFrame
- Baseline
- description
- Self-questionnaire by the patient and the partner
- measure
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient presenting with histologically confirmed prostate cancer. * Patient eligible to start GnRH agonist therapy, either as monotherapy or adjuvant therapy, and for whom one of these treatments was selected voluntarily by the urologist, prior to the start of the study. * Patient currently living with the same partner for at least 6 months. * Patient and partner capable of reading, understanding and returning an evaluation self-questionnaire 6 months after the initial consultation. * Patient giving its written consent to participate to the study. Exclusion Criteria: * The subject is participating in another clinical trial. * Patient who has received a GnRH agonist therapy during the last 2 years.
References
Publications (1)
- RESULTDroupy S, Colson MH, Pello-Leprince-Ringuet N, Perrot V, Descazeaud A. EQUINOXE study: Impact of relational cohesion and sexuality on the quality of life of patients treated with gonadotropin-releasing hormone agonist for prostate cancer. BJUI Compass. 2021 Oct 19;3(1):45-54. doi: 10.1002/bco2.92. eCollection 2022 Jan. PMID 35475155