Clinical trial · Observational
Partial Breast Irradiation for Low-risk Ductal Carcinoma In Situ After Breast-conserving Surgery
Phase II Study of Partial Breast Irradiation for Low-risk Ductal Carcinoma In Situ After Breast-conserving Surgery
NCT02617082CI-TRIAL-00019975unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to evaluate the feasibility and safety of partial breast irradiation for low risk DCIS after breast-conserving surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| partial breast irradiation | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- partial breast irradiation
- interventionNames
- Radiation: partial breast irradiation
Primary outcomes (1)
- measure
- ipsilateral breast tumor recurrence
- timeFrame
- 5 years
Secondary outcomes (5)
- measure
- occurrence of contralateral breast tumor after PBI
- timeFrame
- 5 years
- measure
- Disease free survival
- timeFrame
- 5 years
- measure
- Overall survival
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Female * 18\~65 years old * Pathologically confirmed DCIS, low- or intermediate- grade DCIS: (lesions of ≤2.5 cm diameter, resection margins of at least 3 mm, nuclei grade: 1-2), high grade DCIS: (lesions of ≤1 cm diameter, resection margins of at least 3 mm, nuclei grade: 3) * Treated with breast conserving surgery * Tumor bed is labeled with Titanium clips * No malignancy history * ECOG score 0\~1 * Written informed consent Exclusion Criteria: * DCIS of both breast * invasive breast cancer * Multicentric disease * Patients underwent mastectomy * Previous radiation therapy of breast * Medical contraindication for radiotherapy * Pregnant or nursing * suspicious calcification after surgery
References
Publications (0)
Data not yet available
No reference posted for this study.