Clinical trial · Interventional
Total/Subtotal Colectomy in Ovarian Cancer
A Phase II Study of Total or Subtotal Colectomy in Stage IIIC and Stage IV Epithelial Ovarian, Fallopian Tube, and Primary Peritoneal Cancer (EOC, FTC, PPC)
NCT02595021CI-TRIAL-00023241unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the safety and one year disease-free survival of total or subtotal colectomy and proctocolectomy in stage IIIc and stage IV epithelial ovarian, fallopian tube, and primary peritoneal cancer (EOC, FTC, PPC).
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Epithelial Ovarian Cancer | Ovarian Carcinoma | ALIAS | 0.90 |
| Fallopian Tube Cancer | Malignant Fallopian Tube Neoplasm | ALIAS | 0.90 |
| Primary Peritoneal Carcinoma | Primary Peritoneal Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Secondary Malignant Neoplasm of Large Intestine | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Other Bowel Resection | Procedure | — | UNRESOLVED |
| Total or Subtotal Colectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Total or Subtotal Colectomy
- description
- all patients who underwent total colectomy(removal of the large intestine from ileum to the rectum. After it is removed, the end of the small intestine is sewn to the rectum) or subtotal colectomy(removal of transverse colon, descending colon, sigmoid colon to the rectum. After it is removed, the end of the ascending colon is sewn to the rectum)as part of optimal cytoreductive surgery
- interventionNames
- Procedure: Total or Subtotal Colectomy
- type
- ACTIVE_COMPARATOR
- label
- Other Bowel Resection
- description
- all patients who underwent partial intestinal resection as part of optimal cytoreductive surgery
- interventionNames
- Procedure: Other Bowel Resection
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥18 years and ≤ 75 years. * Epithelial ovarian cancer, fallopian tube cancer, primary peritoneal carcinoma with pathology confirmed International Federation of Gynecology and Obstetrics (FIGO) stage IIIc or IV * Extensive colonic metastasis, tumor involving the major part of bowel surface and/or mesentery * Optimal cytoreductive surgery, including hysterectomy, bilateral salpinges-oophorectomy, omentectomy, and resection of all metastatic lesions, with a residual disease no more than 0.5cm * Eastern Cooperative Oncology Group (ECOG) performance status 0-2. * American Society of Anesthesiologists (ASA) performance 1-2. * Follow-up available. * Written informed consent. Exclusion Criteria: * Low-malignant potential ovarian tumor. * Patient who underwent enterostomy in the surgery procedure. * Tumor involving small intestine alone. * More than 2 anastomoses. * Other condition that could interfere with provision of informed consent, compliance to study procedures, or follow-up. * Prior invasive malignancies within the last 5 years showing activity of disease.
References
Publications (0)
Data not yet available
No reference posted for this study.