Clinical trial · Interventional
Remifentanil Infusion Alone During the Closure Period for Early Emergence Following Craniotomy
Effect of Remifentanil Infusion Alone During the Closure Period for Early Emergence and Hemodynamic Stability in Patients Undergoing Supratentorial Craniotomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Total intravenous anaesthesia using propofol and remifentanil are routinely used drugs for this purpose. The hemodynamic stability and at the same time early emergency are the main goals following neurosurgery. However there is no standard for discontinuation time for manually controlled systems today. The investigators aimed to study the effect of remifentanil infusion alone for early emergence and hemodynamic stability during the closure period in patients undergoing supratentorial craniotomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Supratentorial Neoplasms | Supratentorial Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Propofol | Drug | — | UNRESOLVED |
| Remifentanil | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- group I
- description
- remifentanil
- interventionNames
- Drug: Remifentanil
- type
- EXPERIMENTAL
- label
- group II
- description
- remifentanil, propofol
- interventionNames
- Drug: Remifentanil
- Drug: Propofol
Primary outcomes (1)
- measure
- Time of extubation
- timeFrame
- 3 hours
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * American Society of Anaesthesiologist physical status I-II * Glasgow Coma Scale score of 15 points * Elective supratentorial craniotomy for tumor resection * Supine position Exclusion Criteria: * Obese patient * Brain tumor greater than 30 mm in diameter * Postoperative cranial drainage * Hypertension * Diabetes mellitus * Reoperation * Pregnant * Breast feeding * Allergy to the study medications * History of cranial radiotherapy * Frontal bone flap * Intraoperative neuromonitoring
References
Publications (0)
Data not yet available