Clinical trial · Observational
Primary Culture of Residual Specimens Obtained From Aspiration of Hepatic Tumor to Predict the Prognosis of the Patients
Kaohsiung Medical University Chung-Ho Memorial Hospital
NCT02587793CI-TRIAL-00037337completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this project is to investigate whether the proliferative speeds of cultured cells using our method can be integrated into Barcelona Clinic Liver Cancer (BCLC) staging classification for the possibility of personalized treatment and prediction the outcomes in hepatocellular carcinoma (HCC) patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| not interventional study | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Barcelona Clinic Liver Cancer (BCLC) staging
- description
- The tumor stages of the patient are classified as BCLC stage 0, A, B, C, or D.
- interventionNames
- Other: not interventional study
Primary outcomes (1)
- measure
- survival
- timeFrame
- one year
- description
- Correlation between the proliferative speeds of cultured cells and one year survival of the patients after aspiration of the tumor will be investigated.
Secondary outcomes (1)
- measure
- cancer progression
- timeFrame
- one year
- description
- Correlation between the proliferative speeds of cultured cells and HCC progression one year after aspiration of the tumor will be investigated.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Patients are proven to have HCC based on fine-needle aspiration of the tumor. 2. Patient have residual specimens obtained from fine-needle aspiration of the tumor. 3. Patients agree to participate this study after fully explanation. Exclusion Criteria: 1. Patients are not proven to have HCC based on fine-needle aspiration of the tumor. 2. Patient do not have residual specimens obtained from fine-needle aspiration of the tumor. 3. Patients do not agree to participate this study after fully explanation.
References
Publications (2)
- RESULTLin ZY, Chuang WL, Chuang YH, Yu ML, Hsieh MY, Wang LY, Tsai JF. Discordant influence of amphotericin B on epirubicin cytotoxicity in primary hepatic malignant cells collected by a new primary culture technique. J Gastroenterol Hepatol. 2006 Feb;21(2):398-405. doi: 10.1111/j.1440-1746.2005.04026.x. PMID 16509865
- RESULTLin ZY, Wu CC, Chuang YH, Chuang WL. Clinical utility of a simple primary culture method in hepatocellular carcinoma patients. J Gastroenterol Hepatol. 2015 Feb;30(2):352-7. doi: 10.1111/jgh.12693. PMID 25087586