Clinical trial · Interventional
Taxane Chemotherapy and Nail Toxicity in Women With Breast Cancer; Stage Two: Evaluation of Interventions
NCT02583204CI-TRIAL-00019561unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study compares three strategies to prevent/minimise nail problems occuring in women, with breast cancer, undergoing Taxane chemotherapy. The strategies are: application of nail polish and normal care; application of Onicolife drops and normal care and; normal care only.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Nail Toxicity | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nail polish | Other | — | UNRESOLVED |
| Onicolife nail drops | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- Control - standard care
- description
- Participants will receive standard care regarding nail toxicity. This entails advice to keep nails trim and the provision of a nail oil to massage into the nail daily. Participants will also receive advice in relation to general healthy living.
- type
- EXPERIMENTAL
- label
- Intervention - Oncolife drops
- description
- Participants will receive the same standard care as the control arm, except for the nail drops. The participants will also receive Onicolife nail drops to be applied twice daily.
- interventionNames
- Device: Onicolife nail drops
- type
- EXPERIMENTAL
- label
- Intervention - Nail polish
- description
- Participants will receive the same standard care as the control arm, except for the nail drops. The participants will also receive a dark coloured nail polish to be applied as instructed.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * women over the age of 18 years who have been diagnosed with a breast cancer. * must be receiving adjuvant or neo-adjuvant Taxotere chemotherapy for breast cancer. * participants must be fluent English speakers to be eligible to take part, as there are no resources or additional funding for translators or interpreting services. * Participants must provide informed consent. Exclusion Criteria: * Male patients with a diagnosis of breast cancer * Patients who are non-fluent English speakers * Patients with a known hypersensitivity reaction to nail/ relevant cosmetic products * Previous treatment with taxane chemotherapy with the last two years * Patients with only one upper limb. * Patients with a neurological deficit to the upper limb (eg, stroke affecting one side)
References
Publications (0)
Data not yet available
No reference posted for this study.