Clinical trial · Interventional
An Open Trial of Metacognitive Therapy for Anxiety and Depression in Cancer
An Open Trial of Metacognitive Therapy for Anxiety and Depression in Cancer (OMAC Study)
NCT02580656CI-TRIAL-00029748completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Survival rates in cancer continue to improve, with over 2 million adult cancer survivors in the United Kingdom, projected to increase to 4 million by 2030. Around 25% of these survivors require treatment for clinical levels of emotional distress. The investigators will conduct a phase I open trial to test the potential efficacy of MCT in cancer survivors.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Depression | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Metacognitive Therapy | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Metacognitive Therapy
- description
- Metacognitive Therapy (MCT) is a brief psychological intervention which will be delivered over a course of six, one hour weekly sessions. Treatment will follow a manualised protocol.
- interventionNames
- Behavioral: Metacognitive Therapy
Primary outcomes (1)
- measure
- Hospital Anxiety and Depression Scale (HADS-Total)
- timeFrame
- Change in HADS total following the course of the six week intervention and over the six month follow-up
- description
- A general measure of anxiety and depression used in people
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Cancer diagnosis at least 6 months previously * Scoring \>15 on the Hospital Anxiety and Depression Scale Total * Stable on, or free from, psychotropic medication Exclusion Criteria: * History of psychotic disorder, learning disability, or organic mental disorder * Risk of self-harm or suicide warranting immediate intervention * In palliative phase of treatment * Being considered for risk-reducing or reconstructive surgery within 1 year * Concurrent psychological treatment * Cognitive impairment precluding informed consent or participation
References
Publications (0)
Data not yet available
No reference posted for this study.