Clinical trial · Observational
Pilot Study In Vivo Confocal Microscopy Probe for Cervical Precancer
Pilot Study of the Hand-held In Vivo Confocal Microscopy Probe for Detection of Cervical Intraepithelial Neoplasia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Funding has run out
Summary
Brief summary (as posted)
The goal of this proposal is to determine whether a hand-held confocal microscopy probe may perform better than standard methods in detecting cancer or pre-cancerous abnormalities of the cervix. The confocal probe will provide invivo histopathology-like images of cell morphology and three-dimensional tissue architecture non-invasively in real time.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
| Precancerous Condition | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| In Vivo Confocal Microscopy Probe | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Initial Colposcopy Visit
- description
- Women with a scheduled colposcopy and biopsy appointment at the Women's Clinic at Vancouver General Hospital
- interventionNames
- Device: In Vivo Confocal Microscopy Probe
Primary outcomes (1)
- measure
- Detection of pre-cancer abnormalities of the cervix by the confocal microscopy probe
- timeFrame
- Probe measurements on participant's cervix should take no more than 10 minutes during the clinical visit
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * indicate understanding of the study * provide informed consent to participate * 18 years old or older * not pregnant and have negative urine pregnancy test * be schedule for colposcopy \& biopsy at the Vancouver General Hospital Women's Clinic Exclusion Criteria: * they are breast-feeding * they had an operation to remove their cervix
References
Publications (0)
Data not yet available