Clinical trial · Interventional
The Preemptive Analgesic Efficacy of Nefopam
NCT02561468CI-TRIAL-00021661completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Nefopam is administered as a preemptive analgesic drug to the patient undergoing breast cancer surgery. It will be evaluated whether postoperative acute and chronic pain can be reduced.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasm | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nefopam | Drug | — | UNRESOLVED |
| Saline | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Nefopam
- description
- 20 mg nefopam in 100 ml normal saline is infused before starting operation.
- interventionNames
- Drug: Nefopam
- type
- PLACEBO_COMPARATOR
- label
- Control
- description
- 100 ml normal saline is infused before starting operation.
- interventionNames
- Drug: Saline
Primary outcomes (1)
- measure
- The change of pain numerical rating score from postoperative 30 min until postoperative 3 month
- timeFrame
- Postoperative 30 min, postoperative 1 day, postoperative 1 week, postoperative 3 month
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed with breast cancer * Lumpectomy with axillary lymph node dissection or Lumpectomy with sentinel lymph node biopsy * American Society of Anesthesiologists physical status I or II Exclusion Criteria: * Refusal * Seizure * Cardiac disease * Monoamine oxidase inhibitor user * Urologic disease * Glucoma * Preoperative analgesic drug medication * Pregnancy * Recurred breast cancer patient
References
Publications (0)
Data not yet available
No reference posted for this study.